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Spore Syringes vs. Liquid Culture Syringes

Mushroom cultivation can be an exciting and rewarding hobby, but it’s important to understand the different tools and techniques available, especially when it comes to Psilocybe Cubensis, a species known for its psychedelic properties. In this blog post, we’ll explore the differences between spore syringes and liquid culture syringes and address the legal aspects of using these tools for Psilocybe Cubensis cultivation.

Chapter 1: Spore Syringes – The Seeds of Growth

Notice how the liquid is clear, spores are not visible to the naked eye

What Are Spore Syringes?

Spore syringes are a common and legal way to start the cultivation process with Psilocybe Cubensis. They are precisely what they sound like – syringes filled with mushroom spores suspended in a sterile solution. These spores are the “seeds” of your mushroom cultivation journey. We sell a wide variety of these spores on our site. Here’s a link to our products!

Using Spore Syringes:

  1. Inoculation: Spore syringes are primarily used to inoculate substrates (e.g., grains, agar, or sterilized media). The spores germinate into mycelium, the vegetative part of the fungus.
  2. Multi-Strain Cultivation: You can use different spore syringes to grow multiple strains or varieties of Psilocybe Cubensis.

Chapter 2: Liquid Culture Syringes – A Mycelium Boost

Notice how a cloudiness is obviously visible with a liquid culture syringe. This is the mycelium in the syringe

What Are Liquid Culture Syringes?

Liquid culture syringes contain mycelium suspended in a nutrient-rich liquid solution, offering an advantage over spore syringes. These syringes are not spore-based but rather contain active fungal growth.

Perks to using Liquid Culture Syringes:

  1. Fast Colonization: Liquid culture syringes provide a head start as they contain active mycelium. This leads to faster colonization of your chosen substrate, as opposed to waiting for spores to germinate.
  2. Cloning: You can create liquid cultures from a piece of a mushroom, a clone, or an agar culture. This allows you to maintain the genetic characteristics of a specific mushroom strain.

Chapter 3: Legal Considerations – The Psilocybe Cubensis Dilemma

The legal status of Psilocybe Cubensis varies depending on your location. In many countries, the possession, cultivation, or consumption of Psilocybe Cubensis is either illegal or regulated. Spore syringes are generally considered legal in many places because they contain no active substances, just spores.

Liquid culture syringes, on the other hand, may be seen as more problematic, as they contain active mycelium, which can be used for cultivation. If you’re considering using Psilocybe Cubensis for any purpose, it’s essential to research and understand the specific laws in your area, as they can change from place to place.

Chapter 4: Best Practices

When working with Psilocybe Cubensis, or any mushroom species for that matter, here are some best practices to consider:

  1. Legal Compliance: Always prioritize legal compliance and research the specific laws in your area regarding Psilocybe Cubensis.
  2. Sterility: Maintain a sterile work environment when using either spore syringes or liquid culture syringes to avoid contamination during cultivation.
  3. Responsible Cultivation: If you’re cultivating Psilocybe Cubensis, do so responsibly and with consideration of the potential risks and legal consequences.
  4. Knowledge and Education: Educate yourself about the cultivation process, the specific requirements of the species, and responsible use.


In conclusion, understanding the differences between spore syringes and liquid culture syringes is vital when cultivating Psilocybe Cubensis or any mushroom species. While spore syringes are generally considered legal and are a great way to start your journey, liquid culture syringes offer advantages in terms of faster colonization and strain preservation. However, it’s crucial to research and adhere to the laws governing Psilocybe Cubensis in your area and approach cultivation with care and responsibility.

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Mesquite Weekend Follow-up: Oyster Mushroom Workshop

Hi there! Welcome to my website! If you’re looking for more information on the Mesquite Weekend Oyster Mushroom Workshop then you are in the right place! If you just found this page otherwise, I recently hosted a workshop in which participants combined ingredients to create ready-to-go oyster mushroom grow bags. This is the recipe for the exact grow bags that we made in the workshop.

If this is all new to you, here’s a list of key terms to help:

  • Mycelium – An interconnected mosaic of thin filaments called hyphae that collect food, water, and nutrients to nourish the fungus
  • Fruiting Body – the spore-producing organ of a fungus, often seen as a mushroom or toadstool.
  • Substrate – a medium that allows mushroom mycelium to develop and establish itself
  • Spawn – Mycelium colonized over a substrate that is used to further inoculate more substrate
  • Fruiting Conditions – creating an environment of high humidity and more fresh air exchange to promote the fruiting stage of the mushroom

The recipe for each grow bag is as follows:

Non-Sterile Oyster Mushroom Grow Bag
Using a 1 Gallon Ziplock bag, add:
4 cups Pelletized newspaper
¼ cup rabbit/guinea pig food
4 cups water
> > > Mix everything up good and wait a few minutes for absorption
Add ¼ cup spawn (we used colonized grain spawn)
Mix thoroughly and seal bag shut (without pushing the excess air out)
A fully colonized block of Oyster Mushroom spawn

You’re almost there! Once you mix it all up, you just need to place your grow bag out of direct sunlight at room temperature and wait 2-4 weeks for the mycelium to colonize the substrate. Once the mycelium appears to have colonized all of the substrate (see image above), folks can initiate fruiting by pushing any air out of the bag, resealing and cutting a small “X” in the bag. Oyster mushrooms are naturally a side-fruiting mushroom, growing horizontally from the mycelium. For best fruiting results, I’d recommend standing your bag up and cutting the slit in the side of the bag.

While in fruiting conditions, mushrooms require high humidity to retain the moisture in the fruiting bodies. To make a more humid environment for your mushies, you can make a small tent using a plastic grocery bag and a few sticks/paint stirrers to support the grocery bag up off of the grow bag. Spray water in the grocery bag with a mister every day or so to keep the tent humid.

That’s pretty much all there is to it!

If you want to go a step further, you can create a Shotgun Fruiting Chamber which holds a steady humidity a little better than a plastic bag and looks much nicer as well. They’re pretty easy to make, all you do is get a plastic tote with some holes drilled in it for air flow, add about 1″ of perlite in the bottom, soak the perlite with water, and place your ready-to-fruit grow bag inside the tote and place the lid on!

A Simple Shotgun Fruiting Chamber (SGFC)
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What is Uncle Bens Tek?

90 Second Mycology – An Absolute BEGINNER’S GUIDE to Get Started Growing Mushrooms \\ For Leisure, Business, or Novelty!

Uncle Ben’s Tek Explained

Cultivating gourmet mushrooms used to be a complex process, requiring laboratory equipment like Laminar Flow hoods and HEPA-filtered grow rooms. Then one day, somewhere deep in the web of dense cultural exchanges happening through various forums, emerged a new technique that rose to the height of mainstream…

This new technique (often referred to as a ‘Tek’) is known as Uncle Bens Tek. This tek eliminates the need for expensive equipment by utilizing the latest play on human laziness: ready-to-eat rice that is sterilized and hydrated. These bags can be purchased at any local grocery store and contain the perfect medium for colonizing gourmet mushroom mycelium. By simply injecting these bags with a syringe containing your favorite gourmet spores, and adding a gas-exchange hole, you can have mycelium producing in a few days. Before uncle ben’s tek, achieving this step was the hardest part as the mycelium is weaker than most bacteria and molds during the growth period. This also allows for a very mobile setup that is discrete and low-maintenance, allowing anyone anywhere to give growing their own gourmet mushrooms a shot without much upstart cost.

Need more information?

Here is a good reddit guide on the official r/UncleBens subreddit

Thank you for reading, written by Phillip